Brand Name: Ancavaz
Composition:
Each Ancavaz 10/10 mg Film tablet contains: Amlodipine besylate / Perindopril arginine
Therapeutic Indications:
- As substitution therapy for the treatment of hypertension and/or
- Stable coronary heart disease in patients already controlled with separate doses of perindopril and amlodipine, given concurrently at the same dose level. Treatment should not be initiated with this combination
Dosage and Administration
- . Recommended treatment is one tablet per day as a single dose, preferably to be taken in the morning and before a meal
Contraindications
- In patients with a history of previous hypersensitivity to either of the active ingredients; perindopril or amlodipine, ACE inhibitors, dihydropyridines or excipient ingredients
- During pregnancy and for lactating women.
Warnings and precautions
- Lactose intolerance
- Hyperkalaemia
- Patients with diabetes
- Lithium
- Potassium sparing medicines, potassium supplements or potassium-containing salt substitutes
- Dantrolene
- Angioedema
- Anaphylactoid reactions during low-density lipoproteins (LDL) apheresis and haemodialysis
- Anaphylactic reactions during desensitization
- Hypotension
- Renovascular hypertension
- Kidney transplantation
- Dual blockade of the renin-angiotensin-aldosterone system (RAAS)
- Proteinuria
- Aortic or mitral valve Stenosis / hypertrophic cardiomyopathy
- Primary aldosteronism
Undesirable Effects
- oedema,
- somnolence,
- dizziness,
- headache
Pharmacological Properties
Ancavaz contains perindopril arginine, an angiotensin converting enzyme inhibitor, and amlodipine, a dihydropyridine calcium channel blocker
Packaging
Ancavaz : Box containing 2 blisters of 10 tablets each
