Nexicure-20
Nexicure-40
Nexicure-20
Nexicure-40

Nexicure MUPS

Pharmaceutical

Product Details:

Leaflet

Brand Name: Nexicure Film Coated MUPS tablet

Composition:

Each Nexicure 40mg Film Coated MUPS tablet contains: Esomeprazole  ............. 40 mg

Each Nexicure 20mg Film Coated MUPS tablet contains: Esomeprazole .............. 20 mg

Each Nexicure sachet contains: Esomeprazole  .......................................................20 mg

Each Nexicure sachet contains: Esomeprazole  ........................................................10 mg

Each Nexicure sachet contains: Esomeprazole  ..........................................................5 mg

Each Nexicure sachet contains: Esomeprazole  .......................................................2.5 mg

Therapeutic Indications:                 

  • Gastroesophageal reflux disease (GERD)
  • Erosive reflux oesophagitis.
  • Treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome
  • Prolonged treatment after prevention of rebleeding of ulcers with intravenous PPI.
  • To treat heartburn caused by gastroesophageal reflux disease (GERD)
  • For healing of Helicobacter pylori-associated duodenal ulcers
  • Prevention of relapse of duodenal ulcer in patients of Helicobacter pylori-associated ulcers.
  • Treatment of gastric ulcers caused by medicines called NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).
  • Prevention of gastric ulcers associated with NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). In patients at risk.

Dosage and Administration:             

  • 40mg once daily for GERD
  • 40 mg twice a day for Zollinger-Ellison syndrome
  • In combination with appropriate anti-bacterial therapeutic regimens for the eradication of

Helicobacter pylori.

  • 40 mg tablet once a day for 4 weeks for prolonged treatment after prevention of rebleeding of ulcers with intravenous PPI.
  • Long treatment of healed esophagitis is Nexicure 20 mg once a day.
  • one Nexicure 20 mg once a day for patients without esophagitis.

For adults and adolescents from age 12:    

  • 20mg tablet twice a day for one week to treat ulcers caused by Helicobacter pylori infection and to prevent relapse.
  • Healing of gastric ulcers associated with NSAIDs therapy is Nexicure 20 mg once a day for 4-8 weeks.
  • Prevention of gastric ulcers and associated with NSAIDs is Nexicure 20 mg once a day.
  • 1 to 11 years 10 mg or 20 mg Once daily for up to 8 weeks.
  • 1 month to less than 1 year: 2.5 mg, 5 mg, or 10 mg (based on weight). Once daily, up to 6 weeks for erosive esophagitis (EE) due to acid-mediated GERD only.

Contraindications:           

Do not take Nexicure:

  • If you are allergic to esomeprazole or any of the other ingredients of this medicine (listed in insert leaflets) or allergic to other proton pump inhibitor medicines (e.g. pantoprazole, lansoprazole, rabeprazole, omeprazole).
  • If you are taking a medicine containing nelfinavir (used to treat HIV infection).
  • If you are not sure, talk to your doctor or pharmacist before taking Nexicure.

Warnings and precautions:      

Talk to your doctor or pharmacist before taking Nexicure:

  • If you have severe liver problems or severe kidney problems.
  • If you have ever had a skin reaction after treatment with a medicine similar to Nexicure that reduces stomach acid.
  • If you are due to have a specific blood test (Chromogranin A).

Undesirable Effects:    

  • Taking a proton pump inhibitor like Nexicure, especially over a period of more than one year, may slightly increase your risk of fracture in the hip, wrist, or spine. Tell your doctor if you have osteoporosis or if you are taking corticosteroids (which can increase the risk of osteoporosis).

Pharmacological Properties:      

Nexicure belongs to the proton pump inhibitor group and is a medication that reduces stomach acid.

Packaging:              

Nexicure 40mg Tablets: Box containing 2 blisters of 10 tablets each.

Nexicure 20mg Tablets: Box containing 2 blisters of 10 tablets each.

Nexicure 20 mg Sachet: contains 10 sachets per pack.

Nexicure 10 mg Sachet: contains 10 sachets per pack.

Nexicure 5 mg Sachet: contains 10 sachets per pack.

Nexicure 2.5 mg Sachet: contains 10 sachets per pack.