Hypersensitivity to the active substances, to dihydropyridine derivatives, or to any of the excipients
Severe hepatic impairment, biliary cirrhosis or cholestasis.
Concomitant use of Exforge with aliskiren-containing products in patients with diabetes mellitus or renal impairment (GFR <60 ml/min/1.73 m2)
Second and third trimesters of pregnancy
Shock (including cardiogenic shock).
Obstruction of the outflow tract of the left ventricle (e.g. hypertrophic obstructive cardiomyopathy and high grade aortic stenosis).
Hemodynamically unstable heart failure after acute myocardial infarction.
Warnings and precautions
Sodium- and/or volume-depleted patients
Renal artery stenosis
Heart failure/post-myocardial infarction
Aortic and mitral valve stenosis
Dual blockade of the renin-angiotensin-aldosterone system (RAAS)
nasopharyngitis, influenza, hypersensitivity, headache, syncope, orthostatic hypotension, oedema, pitting oedema, facial oedema, oedema peripheral, fatigue, flushing, asthenia and hot flush
Zetakardoval combines two antihypertensive compounds with complementary mechanisms to control blood pressure in patients with essential hypertension: amlodipine belongs to the calcium antagonist class and valsartan to the angiotensin II antagonist class of medicines. The combination of these substances has an additive antihypertensive effect, reducing blood pressure to a greater degree than either component alone
Zetakardoval Tablet: Box containing 3 blisters of 10 tablets each
36 Al Sheikh Mohammed Al Nadi St., Off Mostafa El Nahaas St. 6th District.
Nasr City, Cairo, Egypt.