







Zetazolex
Pharmaceutical
Product Details:
- Active: Brexpiprazole
- Pack of 30
- Form: Tablet
- Concentration: 0.25mg , 0.5mg , 1mg , 2mg , 3mg , 4mg
- Speciality: All Specialities, CNS
Brand Name: Zetazolex 1mg Tablet
Composition
Each Zetazolex 1mg tablet contains: Brexpiprazole ..................................................... 1 mg.
Each Zetazolex 2mg tablet contains: Brexpiprazole ................................................... 2 mg
Each Zetazolex 3mg tablet contains: Brexpiprazole .................................................... 3 mg
Each Zetazolex 4mg tablet contains: Brexpiprazole ................................................... 4 mg.
Therapeutic Indications
○ Use as adjunctive therapy to antidepressants for the treatment of major depressive disorder (MDD) in adults.
○ Treatment of schizophrenia in adults and pediatric patients ages 13 years and older.
Dosage and Administration:
Administer ZetaZolex once daily with or without food
Indication | Starting Dose | Recommended Dose | Maximum Dose |
MDD Adults | 0.5 mg/day or 1 mg/day | Recommended Dose | 3 mg/day
|
Schizophrenia Adults | 1 mg/day | 2 to 4 mg/day | 4 mg/day |
Schizophrenia Pediatric (13 - 17 years) | 0.5 mg/day | 2 to 4 mg/day | 4 mg/day
|
Contraindications:
Warnings and precautions:
Seizures: Use cautiously in patients with a history of seizures or with conditions that lower
Undesirable Effects:
Pharmacological Properties:
The mechanism of action of brexpiprazole in the treatment of major depressive disorder or schizophrenia is unknown. However, the efficacy of brexpiprazole may be mediated through a combination of partial agonist activity at serotonin 5-HT1A and dopamine D2 receptors, and antagonist activity at serotonin 5-HT2A receptors.
Packaging:
Zetazolex 1mg Tablets: Box containing 3 blisters of 10 tablets each.
Zetazolex 2mg Tablets: Box containing 3 blisters of 10 tablets each.
Zetazolex 3mg Tablets: Box containing 3 blisters of 10 tablets each.
Zetazolex 4mg Tablets: Box containing 3 blisters of 10 tablets each.
36 Al Sheikh Mohammed Al Nadi St., Off Mostafa El Nahaas St. 6th District. Nasr City, Cairo, Egypt.